node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
IQ63_22475 | dnaN_1 | IQ63_22475 | IQ63_44260 | ATP-dependent helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA polymerase III subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.909 |
IQ63_22475 | dnaN_2 | IQ63_22475 | IQ63_25315 | ATP-dependent helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.922 |
IQ63_22475 | recA | IQ63_22475 | IQ63_22660 | ATP-dependent helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Recombinase RecA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.782 |
IQ63_22475 | recD2_2 | IQ63_22475 | IQ63_14460 | ATP-dependent helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Helicase; DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity; Belongs to the RecD family. RecD-like subfamily. | 0.622 |
IQ63_22475 | recQ_1 | IQ63_22475 | IQ63_22415 | ATP-dependent helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. | ATP-dependent DNA helicase RecQ; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.718 |
IQ63_22475 | recQ_2 | IQ63_22475 | IQ63_02000 | ATP-dependent helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. | ATP-dependent DNA helicase RecQ; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.718 |
IQ63_22475 | topA | IQ63_22475 | IQ63_17795 | ATP-dependent helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.923 |
IQ63_22475 | truB | IQ63_22475 | IQ63_03925 | ATP-dependent helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. | tRNA pseudouridine synthase B; Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs; Belongs to the pseudouridine synthase TruB family. Type 1 subfamily. | 0.882 |
IQ63_22475 | uvrD2 | IQ63_22475 | IQ63_23400 | ATP-dependent helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. | ATP-dependent DNA helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.908 |
dnaN_1 | IQ63_22475 | IQ63_44260 | IQ63_22475 | DNA polymerase III subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology. | ATP-dependent helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.909 |
dnaN_1 | dnaN_2 | IQ63_44260 | IQ63_25315 | DNA polymerase III subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | 0.893 |
dnaN_1 | recA | IQ63_44260 | IQ63_22660 | DNA polymerase III subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology. | Recombinase RecA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.950 |
dnaN_1 | recD2_2 | IQ63_44260 | IQ63_14460 | DNA polymerase III subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology. | Helicase; DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity; Belongs to the RecD family. RecD-like subfamily. | 0.773 |
dnaN_1 | recQ_1 | IQ63_44260 | IQ63_22415 | DNA polymerase III subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology. | ATP-dependent DNA helicase RecQ; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.834 |
dnaN_1 | recQ_2 | IQ63_44260 | IQ63_02000 | DNA polymerase III subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology. | ATP-dependent DNA helicase RecQ; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.834 |
dnaN_1 | topA | IQ63_44260 | IQ63_17795 | DNA polymerase III subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA- (5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supe [...] | 0.839 |
dnaN_1 | uvrD2 | IQ63_44260 | IQ63_23400 | DNA polymerase III subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology. | ATP-dependent DNA helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.997 |
dnaN_2 | IQ63_22475 | IQ63_25315 | IQ63_22475 | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | ATP-dependent helicase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.922 |
dnaN_2 | dnaN_1 | IQ63_25315 | IQ63_44260 | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | DNA polymerase III subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.893 |
dnaN_2 | recA | IQ63_25315 | IQ63_22660 | DNA polymerase III subunit beta; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...] | Recombinase RecA; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family. | 0.957 |