STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
IQ63_14695Cob(I)yrinic acid a,c-diamide adenosyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Cob(I)alamin adenosyltransferase family. (190 aa)    
Predicted Functional Partners:
cobP
Adenosylcobinamide kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.936
cobN
Cobalamin biosynthesis protein CobN; With CobST catalyzes the formation of cobyrinic acid a,c-diamide from hydrogenobyrinic acid a,c-diamide in an ATP-dependent manner; involved in porphyrin and chlorophyll metabolism; vitamin B12 metabolism; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.928
cobO
Cobinamide adenolsyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.927
IQ63_01730
CMP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.918
cobQ
Cobalamin biosynthesis protein CobQ; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily.
  
 
 0.910
cobD
Cobalamin biosynthesis protein CobD; Converts cobyric acid to cobinamide by the addition of aminopropanol on the F carboxylic group.
    
 0.908
cobB_2
Cobyrinic acid ac-diamide synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.907
hisC2
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.743
cobD_1
Aminotransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.743
cbiF
Precorrin-4 C11-methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.719
Your Current Organism:
Streptomyces acidiscabies
NCBI taxonomy Id: 42234
Other names: ATCC 49003, DSM 41668, ICMP 12536, JCM 7913, KCTC 9736, LMG 19856, LMG:19856, NRRL B-16524, S. acidiscabies, Streptomyces acidiscabiei, strain RL-110
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