STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pkn1_5Serine/threonine protein kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (318 aa)    
Predicted Functional Partners:
egtD
histidyl-tRNA synthetase; Catalyzes the SAM-dependent triple methylation of the alpha- amino group of histidine to form hercynine, a step in the biosynthesis pathway of ergothioneine; Belongs to the methyltransferase superfamily. EgtD family.
 
 
 0.922
IQ63_14915
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.889
ribA_4
GTP cyclohydrolase; Catalyzes the conversion of GTP to 2,5-diamino-6- ribosylamino-4(3H)-pyrimidinone 5'-phosphate (DARP), formate and pyrophosphate; Belongs to the GTP cyclohydrolase II family.
       0.791
atsA
Twin-arginine translocation pathway signal protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
   0.748
pkn1_4
Sulfatase-modifying factor protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   
 0.743
gshA_2
Glutamate--cysteine ligase; Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC). This compound is used as substrate for the biosynthesis of the low- molecular thiol compound ergothioneine.
  
  
 0.722
IQ63_03660
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
   0.589
IQ63_29475
Hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
   0.589
IQ63_34515
Alpha-galactosidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
   0.589
IQ63_34285
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    0.564
Your Current Organism:
Streptomyces acidiscabies
NCBI taxonomy Id: 42234
Other names: ATCC 49003, DSM 41668, ICMP 12536, JCM 7913, KCTC 9736, LMG 19856, LMG:19856, NRRL B-16524, S. acidiscabies, Streptomyces acidiscabiei, strain RL-110
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