STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
kynUKynureninase; Catalyzes the cleavage of L-kynurenine (L-Kyn) and L-3- hydroxykynurenine (L-3OHKyn) into anthranilic acid (AA) and 3- hydroxyanthranilic acid (3-OHAA), respectively. (395 aa)    
Predicted Functional Partners:
kynA
Tryptophan 2,3-dioxygenase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.
 
 
 0.999
IQ63_17295
Lipase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 
 0.966
IQ63_12020
Cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.944
IQ63_40755
Cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.944
katE
Hydroperoxidase; Catalase HPII; monofunctional catalase that decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.890
mlhB_2
Alpha/beta hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.699
nlhH_1
Esterase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.699
nlhH_2
Esterase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.699
nlhH_5
Esterase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.699
IQ63_17300
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.676
Your Current Organism:
Streptomyces acidiscabies
NCBI taxonomy Id: 42234
Other names: ATCC 49003, DSM 41668, ICMP 12536, JCM 7913, KCTC 9736, LMG 19856, LMG:19856, NRRL B-16524, S. acidiscabies, Streptomyces acidiscabiei, strain RL-110
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