STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ptpA_2Peptide hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (597 aa)    
Predicted Functional Partners:
IQ63_17545
Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.774
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
    
  0.700
IQ63_16685
ABC transporter substrate-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.680
guaB_2
Inosine-5-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
  
 
  0.676
ptsG_3-2
PTS glucose transporter subunit IIA; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 
 0.673
IQ63_35975
XRE family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.613
IQ63_43325
Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.552
IQ63_25565
Regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.507
IQ63_06475
Metallophosphoesterase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.498
IQ63_17640
LysR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.483
Your Current Organism:
Streptomyces acidiscabies
NCBI taxonomy Id: 42234
Other names: ATCC 49003, DSM 41668, ICMP 12536, JCM 7913, KCTC 9736, LMG 19856, LMG:19856, NRRL B-16524, S. acidiscabies, Streptomyces acidiscabiei, strain RL-110
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