STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nhaApH-dependent sodium/proton antiporter; Na(+)/H(+) antiporter that extrudes sodium in exchange for external protons; Belongs to the NhaA Na(+)/H(+) (TC 2.A.33) antiporter family. (470 aa)    
Predicted Functional Partners:
acsA_3
acetyl-CoA synthetase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
       0.734
IQ63_17685
Transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.709
IQ63_17680
Alpha/beta hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.702
IQ63_03595
Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
    0.609
IQ63_08620
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
    0.609
IQ63_16645
Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
    0.609
IQ63_22970
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
    0.609
IQ63_34005
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
    0.609
IQ63_40455
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
    0.609
mscL
Mechanosensitive ion channel protein; Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.
     
 0.528
Your Current Organism:
Streptomyces acidiscabies
NCBI taxonomy Id: 42234
Other names: ATCC 49003, DSM 41668, ICMP 12536, JCM 7913, KCTC 9736, LMG 19856, LMG:19856, NRRL B-16524, S. acidiscabies, Streptomyces acidiscabiei, strain RL-110
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