Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
IQ63_18985Sarcosine oxidase subunit gamma; Derived by automated computational analysis using gene prediction method: Protein Homology. (199 aa)    
Predicted Functional Partners:
IQ63_18975
Sarcosine oxidase subunit delta; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.999
soxB_1
Sarcosine oxidase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.998
gcvT_1
Ferredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GcvT family.
 
 0.998
mlr_1
Sarcosine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GcvT family.
 
 0.997
thcD_2
Oxidoreductase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.947
glyA2_1
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
  
 
 0.935
soxA_2
Sarcosine oxidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.929
IQ63_41565
Amino acid oxidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.929
gcvT_2
Glycine cleavage system protein T; The glycine cleavage system catalyzes the degradation of glycine.
  
 0.928
mlr_2
Sarcosine oxidase subunit beta; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.910
Your Current Organism:
Streptomyces acidiscabies
NCBI taxonomy Id: 42234
Other names: ATCC 49003, DSM 41668, ICMP 12536, JCM 7913, KCTC 9736, LMG 19856, LMG:19856, NRRL B-16524, S. acidiscabies, Streptomyces acidiscabiei, strain RL-110
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