Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
ydcR_1GntR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology. (431 aa)    
Predicted Functional Partners:
gltB_3
Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
  0.776
dapA_1
Dihydrodipicolinate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the DapA family.
    
  0.769
gcvP
Glycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
   
 
 0.732
IQ63_37595
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
  
 
 0.696
kgd
Alpha-ketoglutarate decarboxylase; Kgd; produces succinic semialdehyde; part of alternative pathway from alpha-ketoglutarate to succinate; essential for normal growth; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.693
mlr_1
Sarcosine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the GcvT family.
  
 
 0.654
trpE_1
Anthranilate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.653
phnA
Anthranilate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.653
pabB_1
Anthranilate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.653
IQ63_11825
Dimethylmenaquinone methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
  0.646
Your Current Organism:
Streptomyces acidiscabies
NCBI taxonomy Id: 42234
Other names: ATCC 49003, DSM 41668, ICMP 12536, JCM 7913, KCTC 9736, LMG 19856, LMG:19856, NRRL B-16524, S. acidiscabies, Streptomyces acidiscabiei, strain RL-110
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