STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
vgb_2Virginiamycin B lyase; Inactivates the type B streptogramin antibiotics by linearizing the lactone ring at the ester linkage, generating a free phenylglycine carboxylate and converting the threonyl moiety into 2- amino-butenoic acid. (299 aa)    
Predicted Functional Partners:
vatD
Acetyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.764
rpoA
DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
      
 0.728
IQ63_15550
Restriction endonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.581
IQ63_45115
Erythromycin esterase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   
 0.574
IQ63_36195
Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.546
azoB_8
Capsule biosynthesis protein CapD; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.532
carB_1
Adenine methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family.
  
   
 0.531
choD
Cholesterol oxidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   
 0.519
IQ63_02440
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.486
dapA_5
Dihydrodipicolinate synthase; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).
      
 0.485
Your Current Organism:
Streptomyces acidiscabies
NCBI taxonomy Id: 42234
Other names: ATCC 49003, DSM 41668, ICMP 12536, JCM 7913, KCTC 9736, LMG 19856, LMG:19856, NRRL B-16524, S. acidiscabies, Streptomyces acidiscabiei, strain RL-110
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