STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
IQ63_22225Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (235 aa)    
Predicted Functional Partners:
gyrB
DNA topoisomerase IV subunit B; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 
 0.594
gyrBR
DNA gyrase subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
    
 
 0.594
rsbU_8
PAS/PAC sensor protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.536
IQ63_35375
Transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.536
IQ63_16745
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
   0.485
IQ63_37060
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
   0.485
sprD_1
Protease; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
   0.460
rsbP_3
Serine/threonine protein phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
  0.457
alpha-LP_1
Serine protease; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
   0.456
IQ63_23910
Regulatory protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
  0.448
Your Current Organism:
Streptomyces acidiscabies
NCBI taxonomy Id: 42234
Other names: ATCC 49003, DSM 41668, ICMP 12536, JCM 7913, KCTC 9736, LMG 19856, LMG:19856, NRRL B-16524, S. acidiscabies, Streptomyces acidiscabiei, strain RL-110
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