STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lysA_1Diaminopimelate decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology. (480 aa)    
Predicted Functional Partners:
dapF
Diaminopimelate epimerase; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan.
 
 0.977
lysA_2
Diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine.
  
  
 
0.914
btrK
Diaminopimelate decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 
0.908
IQ63_32150
ATP-binding protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.903
murE
UDP-N-acetylmuramoylalanyl-D-glutamate--2, 6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily.
     
 0.897
iaaM
Amine oxidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.890
IQ63_42145
Saccharopine dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.888
IQ63_24190
Diaminopimelate epimerase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.879
kefF
NAD(P)H dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
  0.875
dapE_5
Acetyl-lysine deacetylase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.827
Your Current Organism:
Streptomyces acidiscabies
NCBI taxonomy Id: 42234
Other names: ATCC 49003, DSM 41668, ICMP 12536, JCM 7913, KCTC 9736, LMG 19856, LMG:19856, NRRL B-16524, S. acidiscabies, Streptomyces acidiscabiei, strain RL-110
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