STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
IQ63_23285Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (130 aa)    
Predicted Functional Partners:
gltB_3
Glutamate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.864
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
    
 0.842
korA
2-oxoglutarate ferredoxin oxidoreductase subunit alpha; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
  0.776
hisN_2
Histidinol phosphatase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.766
perR
Fur family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the Fur family.
       0.752
guaB_2
Inosine-5-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
    
 0.739
luxQ_2
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.727
slmA_3
TetR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.704
guaB_3
Inosine-5-monophosphate dehydrogenase; Catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.666
neuA
Transferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.500
Your Current Organism:
Streptomyces acidiscabies
NCBI taxonomy Id: 42234
Other names: ATCC 49003, DSM 41668, ICMP 12536, JCM 7913, KCTC 9736, LMG 19856, LMG:19856, NRRL B-16524, S. acidiscabies, Streptomyces acidiscabiei, strain RL-110
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