node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
IQ63_23655 | folP2 | IQ63_23655 | IQ63_23660 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.793 |
IQ63_23655 | tag | IQ63_23655 | IQ63_23650 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 3-methyladenine DNA glycosylase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.876 |
alkA | dinB | IQ63_42800 | IQ63_13895 | DNA-3-methyladenine glycosylase; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA polymerase IV; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. | 0.821 |
alkA | fpg1 | IQ63_42800 | IQ63_03350 | DNA-3-methyladenine glycosylase; Derived by automated computational analysis using gene prediction method: Protein Homology. | formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | 0.483 |
alkA | mutY | IQ63_42800 | IQ63_08695 | DNA-3-methyladenine glycosylase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Adenine glycosylase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.494 |
alkA | ogt_1 | IQ63_42800 | IQ63_42795 | DNA-3-methyladenine glycosylase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Cysteine methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. | 0.971 |
alkA | polA_1 | IQ63_42800 | IQ63_07140 | DNA-3-methyladenine glycosylase; Derived by automated computational analysis using gene prediction method: Protein Homology. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.809 |
alkA | tag | IQ63_42800 | IQ63_23650 | DNA-3-methyladenine glycosylase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 3-methyladenine DNA glycosylase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.538 |
argR | tag | IQ63_35465 | IQ63_23650 | Arginine repressor; Regulates arginine biosynthesis genes. | 3-methyladenine DNA glycosylase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.405 |
dinB | alkA | IQ63_13895 | IQ63_42800 | DNA polymerase IV; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. | DNA-3-methyladenine glycosylase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.821 |
dinB | fpg1 | IQ63_13895 | IQ63_03350 | DNA polymerase IV; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. | formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | 0.558 |
dinB | mutY | IQ63_13895 | IQ63_08695 | DNA polymerase IV; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. | Adenine glycosylase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.541 |
dinB | ogt_1 | IQ63_13895 | IQ63_42795 | DNA polymerase IV; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. | Cysteine methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. | 0.444 |
dinB | polA_1 | IQ63_13895 | IQ63_07140 | DNA polymerase IV; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. | DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.930 |
dinB | tag | IQ63_13895 | IQ63_23650 | DNA polymerase IV; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. | 3-methyladenine DNA glycosylase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.545 |
folP2 | IQ63_23655 | IQ63_23660 | IQ63_23655 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.793 |
folP2 | tag | IQ63_23660 | IQ63_23650 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 3-methyladenine DNA glycosylase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.795 |
fpg1 | alkA | IQ63_03350 | IQ63_42800 | formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | DNA-3-methyladenine glycosylase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.483 |
fpg1 | dinB | IQ63_03350 | IQ63_13895 | formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | DNA polymerase IV; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. | 0.558 |
fpg1 | mutY | IQ63_03350 | IQ63_08695 | formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | Adenine glycosylase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.776 |