STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mafSeptum formation protein Maf; Nucleoside triphosphate pyrophosphatase. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. (200 aa)    
Predicted Functional Partners:
IQ63_24755
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.800
kynA
Tryptophan 2,3-dioxygenase; Heme-dependent dioxygenase that catalyzes the oxidative cleavage of the L-tryptophan (L-Trp) pyrrole ring and converts L- tryptophan to N-formyl-L-kynurenine. Catalyzes the oxidative cleavage of the indole moiety.
    
   0.774
accD5_1
methylmalonyl-CoA carboxyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.746
dus
tRNA-dihydrouridine synthase; Catalyzes the synthesis of 5,6-dihydrouridine (D), a modified base found in the D-loop of most tRNAs, via the reduction of the C5-C6 double bond in target uridines; Belongs to the dus family.
 
     0.727
mreC
Rod shape-determining protein MreC; Involved in formation and maintenance of cell shape.
  
  
 0.697
birA_1
biotin--acetyl-CoA-carboxylase ligase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
    0.690
yvdD_2
Lysine decarboxylase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the LOG family.
     
 0.662
IQ63_24740
Adenylate cyclase; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.649
lipB
Octanoyltransferase; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate.
  
   
 0.543
lipA
Radical SAM protein; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.
   
  
 0.512
Your Current Organism:
Streptomyces acidiscabies
NCBI taxonomy Id: 42234
Other names: ATCC 49003, DSM 41668, ICMP 12536, JCM 7913, KCTC 9736, LMG 19856, LMG:19856, NRRL B-16524, S. acidiscabies, Streptomyces acidiscabiei, strain RL-110
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