STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
IQ63_25205Phosphoesterase; Derived by automated computational analysis using gene prediction method: Protein Homology. (191 aa)    
Predicted Functional Partners:
trpS_1
tryptophanyl-tRNA synthetase; Catalyzes the attachment of tryptophan to tRNA(Trp). Belongs to the class-I aminoacyl-tRNA synthetase family.
     
 0.788
IQ63_26215
Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.667
IQ63_43415
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.587
IQ63_21510
Indole-3-glycerol phosphate synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.583
IQ63_00105
acyl-CoA synthetase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.579
IQ63_26220
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.575
IQ63_17490
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.567
IQ63_25215
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.548
IQ63_31610
Membrane protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.540
disA
DNA integrity scanning protein DisA; Has also diadenylate cyclase activity, catalyzing the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP). c-di-AMP acts as a signaling molecule that couples DNA integrity with progression of sporulation. The rise in c-di-AMP level generated by DisA while scanning the chromosome, operates as a positive signal that advances sporulation; upon encountering a lesion, the DisA focus arrests at the damaged site and halts c-di-AMP synthesis.
  
     0.524
Your Current Organism:
Streptomyces acidiscabies
NCBI taxonomy Id: 42234
Other names: ATCC 49003, DSM 41668, ICMP 12536, JCM 7913, KCTC 9736, LMG 19856, LMG:19856, NRRL B-16524, S. acidiscabies, Streptomyces acidiscabiei, strain RL-110
Server load: low (10%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.