STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
IQ63_26115DNA methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. (548 aa)    
Predicted Functional Partners:
IQ63_26110
Type II site-specific deoxyribonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.969
hsdR
Restriction endonuclease subunit R; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.961
IQ63_30725
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.707
uvrB
Excinuclease ABC subunit B; The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate [...]
    
 
 0.610
IQ63_30730
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.603
IQ63_05265
ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
   
 0.584
IQ63_05105
Helicase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.580
recD
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
 0.547
bsr
Biotin transporter BioY; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.542
IQ63_05550
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.510
Your Current Organism:
Streptomyces acidiscabies
NCBI taxonomy Id: 42234
Other names: ATCC 49003, DSM 41668, ICMP 12536, JCM 7913, KCTC 9736, LMG 19856, LMG:19856, NRRL B-16524, S. acidiscabies, Streptomyces acidiscabiei, strain RL-110
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.