Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
IQ63_28040Von Willebrand factor A; Derived by automated computational analysis using gene prediction method: Protein Homology. (388 aa)    
Predicted Functional Partners:
IQ63_28035
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.963
IQ63_28025
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.921
IQ63_28020
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
     0.918
IQ63_28030
ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.916
IQ63_18345
ATPase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
  
 0.863
sucC
succinyl-CoA synthetase subunit beta; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
     
 0.736
sucD
succinyl-CoA synthetase subunit alpha; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
       0.692
pobB_1
Ferredoxin; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
  0.686
IQ63_10875
stearoyl-CoA 9-desaturase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
  0.686
pht2
Iron-sulfur protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
  0.686
Your Current Organism:
Streptomyces acidiscabies
NCBI taxonomy Id: 42234
Other names: ATCC 49003, DSM 41668, ICMP 12536, JCM 7913, KCTC 9736, LMG 19856, LMG:19856, NRRL B-16524, S. acidiscabies, Streptomyces acidiscabiei, strain RL-110
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