STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lieA_1Peptidase S8; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S8 family. (581 aa)    
Predicted Functional Partners:
eccCa1
Secretion protein EccC; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
 0.782
lieA_2
Peptidase M28; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.677
cpt
Peptidase M14; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
   0.672
bprV_1
Protease; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
  
0.591
IQ63_16490
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
   0.542
secY
Preprotein translocase subunit SecY; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.
    
   0.519
IQ63_39500
Chromosome condensation regulator RCC1; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
   0.516
IQ63_39505
Chromosome condensation regulator RCC1; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
   0.516
IQ63_39510
Sialidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
   0.516
IQ63_31145
Beta-xylosidase; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 
   0.513
Your Current Organism:
Streptomyces acidiscabies
NCBI taxonomy Id: 42234
Other names: ATCC 49003, DSM 41668, ICMP 12536, JCM 7913, KCTC 9736, LMG 19856, LMG:19856, NRRL B-16524, S. acidiscabies, Streptomyces acidiscabiei, strain RL-110
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.