STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A317SJW5ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (527 aa)    
Predicted Functional Partners:
A0A317SH37
DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family.
  
 0.969
A0A317SJ16
PIN domain-like protein.
  
 0.963
A0A317SQL3
Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism.
    
 0.963
A0A317SVV5
P-loop containing nucleoside triphosphate hydrolase protein.
  
 0.950
A0A317SPK0
Uncharacterized protein; Belongs to the PI3/PI4-kinase family.
   
 0.938
A0A317SBL8
ERCC4 domain-containing protein.
   
 0.933
A0A317SDZ4
Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing.
  
 0.931
A0A317SJK3
P-loop containing nucleoside triphosphate hydrolase protein.
   
 0.920
A0A317SNL5
Uncharacterized protein.
   
 0.919
A0A317SXM8
RMI1_N domain-containing protein.
    
 0.919
Your Current Organism:
Tuber magnatum
NCBI taxonomy Id: 42249
Other names: T. magnatum, gray truffle, white Piedmont truffle, white truffle
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