| node1 | node2 | node1 annotation | node2 annotation | score |
| A0A317SH37 | A0A317SJW5 | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. | ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. | 0.992 |
| A0A317SH37 | A0A317SMX3 | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. | DNA polymerase. | 0.673 |
| A0A317SH37 | A0A317SNL5 | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. | Uncharacterized protein. | 0.944 |
| A0A317SH37 | A0A317SPK0 | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. | Uncharacterized protein; Belongs to the PI3/PI4-kinase family. | 0.779 |
| A0A317SH37 | A0A317SQL3 | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. | Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. | 0.989 |
| A0A317SH37 | A0A317STQ5 | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. | Replication protein A, subunit RPA32. | 0.966 |
| A0A317SH37 | A0A317SWT3 | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. | ATP-dependent DNA helicase. | 0.992 |
| A0A317SH37 | A0A317SXX7 | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. | 3'-5' exonuclease domain-containing protein. | 0.999 |
| A0A317SH37 | A0A317T255 | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. | Replication factor A protein 3. | 0.865 |
| A0A317SJW5 | A0A317SH37 | ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. | 0.992 |
| A0A317SJW5 | A0A317SMX3 | ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. | DNA polymerase. | 0.729 |
| A0A317SJW5 | A0A317SNL5 | ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. | Uncharacterized protein. | 0.985 |
| A0A317SJW5 | A0A317SPK0 | ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. | Uncharacterized protein; Belongs to the PI3/PI4-kinase family. | 0.976 |
| A0A317SJW5 | A0A317SQL3 | ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. | Replication protein A subunit; As part of the replication protein A (RPA/RP-A), a single- stranded DNA-binding heterotrimeric complex, may play an essential role in DNA replication, recombination and repair. Binds and stabilizes single-stranded DNA intermediates, preventing complementary DNA reannealing and recruiting different proteins involved in DNA metabolism. | 0.992 |
| A0A317SJW5 | A0A317STQ5 | ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. | Replication protein A, subunit RPA32. | 0.969 |
| A0A317SJW5 | A0A317SXX7 | ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. | 3'-5' exonuclease domain-containing protein. | 0.733 |
| A0A317SJW5 | A0A317SZF8 | ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. | DNA helicase; Belongs to the MCM family. | 0.662 |
| A0A317SJW5 | A0A317T255 | ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. | Replication factor A protein 3. | 0.890 |
| A0A317SMX3 | A0A317SH37 | DNA polymerase. | DNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. | 0.673 |
| A0A317SMX3 | A0A317SJW5 | DNA polymerase. | ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. | 0.729 |
