STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A317T2R1Formate dehydrogenase; Catalyzes the NAD(+)-dependent oxidation of formate to carbon dioxide. Formate oxidation is the final step in the methanol oxidation pathway in methylotrophic microorganisms. Has a role in the detoxification of exogenous formate in non-methylotrophic organisms. Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. FDH subfamily. (415 aa)    
Predicted Functional Partners:
A0A317SCZ4
Tryptophan synthase.
    
  0.863
A0A317SM12
S-formylglutathione hydrolase; Serine hydrolase involved in the detoxification of formaldehyde.
     
 0.855
A0A317SZ14
Malate synthase; Belongs to the malate synthase family.
  
 
 0.794
A0A317SYV8
Fumarate hydratase.
  
 
 0.769
A0A317SIQ7
Pyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.
   
 
 0.745
A0A317T247
ATP-utilizing phosphoenolpyruvate carboxykinase.
   
 
 0.738
A0A317SGU1
Bicupin, oxalate decarboxylase/oxidase.
    
 0.737
A0A317SNN6
Kynurenine formamidase; Catalyzes the hydrolysis of N-formyl-L-kynurenine to L- kynurenine, the second step in the kynurenine pathway of tryptophan degradation. Kynurenine may be further oxidized to nicotinic acid, NAD(H) and NADP(H). Required for elimination of toxic metabolites.
   
 
  0.733
A0A317SI74
Malate dehydrogenase.
  
 0.717
A0A317T4I2
Malate dehydrogenase.
  
 0.717
Your Current Organism:
Tuber magnatum
NCBI taxonomy Id: 42249
Other names: T. magnatum, gray truffle, white Piedmont truffle, white truffle
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.