STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A2T6ZM78Uncharacterized protein. (478 aa)    
Predicted Functional Partners:
A0A2T6ZIY9
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
    
 0.806
A0A2T6ZWN4
WD40-repeat-containing domain protein.
    
 0.801
A0A2T6ZZV0
VEFS-Box of polycomb protein-domain-containing protein.
    
 0.788
A0A2T6ZQB9
WD40-repeat-containing domain protein.
    
 0.782
A0A2T7A4Z0
B30.2/SPRY domain-containing protein.
    
 0.760
A0A2T7A5Z2
WD40-repeat-containing domain protein.
    
 0.759
A0A2T7A8K4
Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
    
 0.745
A0A2T7A1P4
Histone H2B; Belongs to the histone H2B family.
    
 0.739
A0A2T6ZGG9
Histone H2A; Belongs to the histone H2A family.
    
 0.694
A0A2T6ZM74
Histone-lysine N-methyltransferase, H3 lysine-79 specific; Histone methyltransferase that specifically methylates histone H3 to form H3K79me. This methylation is required for telomere silencing and for the pachytene checkpoint during the meiotic cell cycle by allowing the recruitment of RAD9 to double strand breaks. Nucleosomes are preferred as substrate compared to free histones.
    
 0.691
Your Current Organism:
Tuber borchii
NCBI taxonomy Id: 42251
Other names: T. borchii, whitish truffle
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.