node1 | node2 | node1 annotation | node2 annotation | score |
A0A2T6ZDD1 | A0A2T6ZFY3 | Flavo protein. | DNA/pantothenate metabolism flavo protein. | 0.948 |
A0A2T6ZDD1 | A0A2T6ZU77 | Flavo protein. | Thymidylate synthase/dCMP hydroxymethylase domain-containing protein. | 0.930 |
A0A2T6ZDD1 | A0A2T6ZZQ4 | Flavo protein. | Uncharacterized protein. | 0.665 |
A0A2T6ZFY3 | A0A2T6ZDD1 | DNA/pantothenate metabolism flavo protein. | Flavo protein. | 0.948 |
A0A2T6ZFY3 | A0A2T6ZU77 | DNA/pantothenate metabolism flavo protein. | Thymidylate synthase/dCMP hydroxymethylase domain-containing protein. | 0.791 |
A0A2T6ZFY3 | A0A2T6ZYV7 | DNA/pantothenate metabolism flavo protein. | Uncharacterized protein. | 0.830 |
A0A2T6ZFY3 | A0A2T6ZZQ4 | DNA/pantothenate metabolism flavo protein. | Uncharacterized protein. | 0.655 |
A0A2T6ZGN1 | A0A2T6ZH66 | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | 0.798 |
A0A2T6ZGN1 | A0A2T6ZJS1 | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Alpha/Beta hydrolase protein. | 0.861 |
A0A2T6ZGN1 | A0A2T6ZU77 | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Thymidylate synthase/dCMP hydroxymethylase domain-containing protein. | 0.905 |
A0A2T6ZGN1 | A0A2T6ZXB7 | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Queuine tRNA-ribosyltransferase accessory subunit 2; Non-catalytic subunit of the queuine tRNA-ribosyltransferase (TGT) that catalyzes the base-exchange of a guanine (G) residue with queuine (Q) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine); Belongs to the queuine tRNA-ribosyltransferase family. QTRT2 subfamily. | 0.519 |
A0A2T6ZGN1 | A0A2T6ZZQ4 | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Uncharacterized protein. | 0.652 |
A0A2T6ZH66 | A0A2T6ZGN1 | Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.798 |
A0A2T6ZH66 | A0A2T6ZU77 | Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | Thymidylate synthase/dCMP hydroxymethylase domain-containing protein. | 0.936 |
A0A2T6ZH66 | A0A2T6ZXB7 | Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | Queuine tRNA-ribosyltransferase accessory subunit 2; Non-catalytic subunit of the queuine tRNA-ribosyltransferase (TGT) that catalyzes the base-exchange of a guanine (G) residue with queuine (Q) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2- cyclopenten-1-yl)amino)methyl)-7-deazaguanosine); Belongs to the queuine tRNA-ribosyltransferase family. QTRT2 subfamily. | 0.805 |
A0A2T6ZH66 | A0A2T6ZZQ4 | Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. | Uncharacterized protein. | 0.790 |
A0A2T6ZJS1 | A0A2T6ZGN1 | Alpha/Beta hydrolase protein. | Inosine triphosphate pyrophosphatase; Pyrophosphatase that hydrolyzes non-canonical purine nucleotides such as inosine triphosphate (ITP), deoxyinosine triphosphate (dITP) or xanthosine 5'-triphosphate (XTP) to their respective monophosphate derivatives. The enzyme does not distinguish between the deoxy- and ribose forms. Probably excludes non-canonical purines from RNA and DNA precursor pools, thus preventing their incorporation into RNA and DNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.861 |
A0A2T6ZJS1 | A0A2T6ZU77 | Alpha/Beta hydrolase protein. | Thymidylate synthase/dCMP hydroxymethylase domain-containing protein. | 0.851 |
A0A2T6ZJS1 | A0A2T6ZZQ4 | Alpha/Beta hydrolase protein. | Uncharacterized protein. | 0.707 |
A0A2T6ZLX9 | A0A2T6ZZQ4 | Mif2/CENP-C like-domain-containing protein. | Uncharacterized protein. | 0.688 |