STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
A0A2T7A714Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (257 aa)    
Predicted Functional Partners:
A0A2T6ZGY2
UmuC domain-containing protein.
   
 0.999
A0A2T7A1H2
ESCO1/2 acetyl-transferase-domain-containing protein.
   
 0.999
A0A2T7A0V7
3'-5' exonuclease domain-containing protein.
  
 0.995
A0A2T7A437
P-loop containing nucleoside triphosphate hydrolase protein.
  
 0.993
FEN1
Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]
   
 0.992
A0A2T7A5L8
DNA polymerase III, clamp loader complex, gamma/delta/delta subunit.
  
 0.989
A0A2T6ZBU3
Muts domain V-domain-containing protein; Component of the post-replicative DNA mismatch repair system (MMR).
   
 0.985
A0A2T6ZCY7
DNA ligase.
   
 0.985
A0A2T6ZVX7
P-loop containing nucleoside triphosphate hydrolase protein.
  
 0.985
A0A2T6ZPH1
DNA polymerase.
  
 0.982
Your Current Organism:
Tuber borchii
NCBI taxonomy Id: 42251
Other names: T. borchii, whitish truffle
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.