STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ALA57766.1Homologs of previously reported genes of unknown function. (359 aa)    
Predicted Functional Partners:
gyrB
DNA gyrase, subunit B; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
   
 
 0.820
ALA57765.1
Hypothetical protein; Homologs of previously reported genes of unknown function.
       0.773
ALA59295.1
Homologs of previously reported genes of unknown function.
  
     0.659
ALA60942.1
Hypothetical protein; Homologs of previously reported genes of unknown function.
  
    0.646
scpA
Segregation and condensation protein A; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpB that pull DNA away from mid-cell into both cell halves.
  
    0.643
scpB
Segregation and condensation protein B; Participates in chromosomal partition during cell division. May act via the formation of a condensin-like complex containing Smc and ScpA that pull DNA away from mid-cell into both cell halves.
  
    0.629
ALA60898.1
Hypothetical protein; Homologs of previously reported genes of unknown function.
  
     0.629
ALA58040.1
Homologs of previously reported genes of unknown function.
  
     0.605
ALA59601.1
Homologs of previously reported genes of unknown function.
  
     0.558
ALA59758.1
Hypothetical protein; Homologs of previously reported genes of unknown function.
  
 
 
 0.556
Your Current Organism:
Nitrospira moscoviensis
NCBI taxonomy Id: 42253
Other names: DSM 10035, N. moscoviensis, Nitrospira moscoviensis Ehrich et al. 2001, strain NSP M-1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.