STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
merAMercuric reductase; Resistance to Hg(2+) in bacteria appears to be governed by a specialized system which includes mercuric reductase. MerA protein is responsible for volatilizing mercury as Hg(0). Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family. (554 aa)    
Predicted Functional Partners:
bkdAB
2-oxoisovalerate dehydrogenase, beta subunit; Function of strongly homologous gene; enzyme.
 
 0.952
aceF
Pyruvate dehydrogenase complex, dihydrolipoyllysine-residue acetyltransferase (E2) component; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 0.939
ALA56500.1
Branched-chain alpha-keto acid dehydrogenase, dihydrolipoamide acyltransferase (E2) component; Function of strongly homologous gene; enzyme.
 0.937
bkdAA
2-oxoisovalerate dehydrogenase, alpha subunit (TPP-binding module); Function of strongly homologous gene; enzyme.
 
 
 0.905
ALA57984.1
Hypothetical protein; Homologs of previously reported genes of unknown function.
       0.773
gcvH
Glycine cleavage system, H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.
 
  
 0.772
ALA57442.1
Homologs of previously reported genes of unknown function.
 
      0.762
prsA
Ribose-phosphate pyrophosphokinase; Involved in the biosynthesis of the central metabolite phospho-alpha-D-ribosyl-1-pyrophosphate (PRPP) via the transfer of pyrophosphoryl group from ATP to 1-hydroxyl of ribose-5-phosphate (Rib- 5-P); Belongs to the ribose-phosphate pyrophosphokinase family. Class I subfamily.
   
 0.721
ALA57987.1
Putative Alkylmercury lyase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; putative enzyme.
     0.705
ALA60632.1
Homologs of previously reported genes of unknown function.
 
      0.644
Your Current Organism:
Nitrospira moscoviensis
NCBI taxonomy Id: 42253
Other names: DSM 10035, N. moscoviensis, Nitrospira moscoviensis Ehrich et al. 2001, strain NSP M-1
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