node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ALA58116.1 | ALA58117.1 | NITMOv2_1696 | NITMOv2_1697 | Hypothetical protein; Homologs of previously reported genes of unknown function. | Hypothetical protein; Homologs of previously reported genes of unknown function. | 0.773 |
ALA58116.1 | ltaA | NITMOv2_1696 | NITMOv2_1698 | Hypothetical protein; Homologs of previously reported genes of unknown function. | L-allo-threonine aldolase. | 0.660 |
ALA58117.1 | ALA58116.1 | NITMOv2_1697 | NITMOv2_1696 | Hypothetical protein; Homologs of previously reported genes of unknown function. | Hypothetical protein; Homologs of previously reported genes of unknown function. | 0.773 |
ALA58117.1 | ltaA | NITMOv2_1697 | NITMOv2_1698 | Hypothetical protein; Homologs of previously reported genes of unknown function. | L-allo-threonine aldolase. | 0.621 |
gcvP | glyA | NITMOv2_0227 | NITMOv2_0125 | Glycine dehydrogenase, glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.997 |
gcvP | kbl | NITMOv2_0227 | NITMOv2_4547 | Glycine dehydrogenase, glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | Glycine C-acetyltransferase; Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA. | 0.945 |
gcvP | ltaA | NITMOv2_0227 | NITMOv2_1698 | Glycine dehydrogenase, glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | L-allo-threonine aldolase. | 0.950 |
gcvP | pucG | NITMOv2_0227 | NITMOv2_1039 | Glycine dehydrogenase, glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | Purine catabolism protein PucG. | 0.927 |
gcvP | thrC | NITMOv2_0227 | NITMOv2_2399 | Glycine dehydrogenase, glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | Threonine synthase. | 0.441 |
gcvP | thrC-2 | NITMOv2_0227 | NITMOv2_4467 | Glycine dehydrogenase, glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | Threonine synthase; Catalyzes the gamma-elimination of phosphate from L- phosphohomoserine and the beta-addition of water to produce L- threonine. | 0.441 |
glyA | gcvP | NITMOv2_0125 | NITMOv2_0227 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Glycine dehydrogenase, glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.997 |
glyA | kbl | NITMOv2_0125 | NITMOv2_4547 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Glycine C-acetyltransferase; Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA. | 0.923 |
glyA | ltaA | NITMOv2_0125 | NITMOv2_1698 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | L-allo-threonine aldolase. | 0.929 |
glyA | pucG | NITMOv2_0125 | NITMOv2_1039 | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Purine catabolism protein PucG. | 0.922 |
kbl | gcvP | NITMOv2_4547 | NITMOv2_0227 | Glycine C-acetyltransferase; Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA. | Glycine dehydrogenase, glycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.945 |
kbl | glyA | NITMOv2_4547 | NITMOv2_0125 | Glycine C-acetyltransferase; Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.923 |
kbl | ltaA | NITMOv2_4547 | NITMOv2_1698 | Glycine C-acetyltransferase; Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA. | L-allo-threonine aldolase. | 0.913 |
kbl | pucG | NITMOv2_4547 | NITMOv2_1039 | Glycine C-acetyltransferase; Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA. | Purine catabolism protein PucG. | 0.909 |
kbl | tdh | NITMOv2_4547 | NITMOv2_4546 | Glycine C-acetyltransferase; Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA. | Threonine 3-dehydrogenase, NAD(P)-binding; Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.993 |
ltaA | ALA58116.1 | NITMOv2_1698 | NITMOv2_1696 | L-allo-threonine aldolase. | Hypothetical protein; Homologs of previously reported genes of unknown function. | 0.660 |