node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ALA59564.1 | engB | NITMOv2_3165 | NITMOv2_4630 | Putative 23S rRNA methyltransferase RlmB; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | Putative GTP-binding protein EngB; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family. | 0.883 |
ALA59564.1 | rplC | NITMOv2_3165 | NITMOv2_1206 | Putative 23S rRNA methyltransferase RlmB; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | 50S ribosomal subunit protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. | 0.878 |
ALA59564.1 | rplM | NITMOv2_3165 | NITMOv2_1762 | Putative 23S rRNA methyltransferase RlmB; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | 50S ribosomal subunit protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. | 0.889 |
ALA59564.1 | rplO | NITMOv2_3165 | NITMOv2_1225 | Putative 23S rRNA methyltransferase RlmB; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | 50S ribosomal subunit protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. | 0.867 |
ALA59564.1 | rplQ | NITMOv2_3165 | NITMOv2_1234 | Putative 23S rRNA methyltransferase RlmB; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | 50S ribosomal subunit protein L17; Function of homologous gene experimentally demonstrated in an other organism; structure. | 0.852 |
ALA59564.1 | rplX | NITMOv2_3165 | NITMOv2_1217 | Putative 23S rRNA methyltransferase RlmB; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | 50S ribosomal subunit protein L24; One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit. | 0.868 |
ALA59564.1 | rsfS | NITMOv2_3165 | NITMOv2_0972 | Putative 23S rRNA methyltransferase RlmB; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | Hypothetical protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. | 0.862 |
ALA59564.1 | trmE | NITMOv2_3165 | NITMOv2_0286 | Putative 23S rRNA methyltransferase RlmB; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | GTPase; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. | 0.901 |
ALA59564.1 | truD | NITMOv2_3165 | NITMOv2_0475 | Putative 23S rRNA methyltransferase RlmB; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | tRNA pseudouridine synthase D; Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs; Belongs to the pseudouridine synthase TruD family. | 0.858 |
ALA59564.1 | ylyB | NITMOv2_3165 | NITMOv2_0302 | Putative 23S rRNA methyltransferase RlmB; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | Putative RNA pseudouridine synthase YlyB; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | 0.883 |
engB | ALA59564.1 | NITMOv2_4630 | NITMOv2_3165 | Putative GTP-binding protein EngB; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family. | Putative 23S rRNA methyltransferase RlmB; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. | 0.883 |
engB | rplC | NITMOv2_4630 | NITMOv2_1206 | Putative GTP-binding protein EngB; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family. | 50S ribosomal subunit protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. | 0.869 |
engB | rplM | NITMOv2_4630 | NITMOv2_1762 | Putative GTP-binding protein EngB; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family. | 50S ribosomal subunit protein L13; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. | 0.862 |
engB | rplO | NITMOv2_4630 | NITMOv2_1225 | Putative GTP-binding protein EngB; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family. | 50S ribosomal subunit protein L15; Binds to the 23S rRNA; Belongs to the universal ribosomal protein uL15 family. | 0.879 |
engB | rplQ | NITMOv2_4630 | NITMOv2_1234 | Putative GTP-binding protein EngB; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family. | 50S ribosomal subunit protein L17; Function of homologous gene experimentally demonstrated in an other organism; structure. | 0.888 |
engB | rplX | NITMOv2_4630 | NITMOv2_1217 | Putative GTP-binding protein EngB; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family. | 50S ribosomal subunit protein L24; One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit. | 0.890 |
engB | rsfS | NITMOv2_4630 | NITMOv2_0972 | Putative GTP-binding protein EngB; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family. | Hypothetical protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. | 0.877 |
engB | trmE | NITMOv2_4630 | NITMOv2_0286 | Putative GTP-binding protein EngB; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family. | GTPase; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. | 0.907 |
engB | truD | NITMOv2_4630 | NITMOv2_0475 | Putative GTP-binding protein EngB; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family. | tRNA pseudouridine synthase D; Responsible for synthesis of pseudouridine from uracil-13 in transfer RNAs; Belongs to the pseudouridine synthase TruD family. | 0.854 |
engB | ylyB | NITMOv2_4630 | NITMOv2_0302 | Putative GTP-binding protein EngB; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family. | Putative RNA pseudouridine synthase YlyB; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. | 0.897 |