PIR protein (Sorex araneus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

PIR

Pirin. (259 aa)

Predicted Functional Partners:

ENSSARP00000006909

0.827

ENSSARP00000003522

0.726

ENSSARP00000011457

0.665

FLT1

0.650

PDGFRA

0.650

FLT3

0.650

KDR

0.650

ENSSARP00000009243

0.631

INSRR

0.631

KCMF1

0.629

Your Current Organism:

Sorex araneus

NCBI taxonomy Id: 42254
Other names: Eurasian shrew, European shrew, S. araneus

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... as an XML summary:

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

... network coordinates:

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSSARP00000003522	ENSSARP00000011457	ENSSARP00000003522	ENSSARP00000011457	annotation not available	annotation not available	0.429
ENSSARP00000003522	FLT1	ENSSARP00000003522	ENSSARP00000000816	annotation not available	Fms related tyrosine kinase 1.	0.447
ENSSARP00000003522	FLT3	ENSSARP00000003522	ENSSARP00000009433	annotation not available	Fms related tyrosine kinase 3.	0.433
ENSSARP00000003522	KDR	ENSSARP00000003522	ENSSARP00000012971	annotation not available	Kinase insert domain receptor.	0.434
ENSSARP00000003522	PDGFRA	ENSSARP00000003522	ENSSARP00000001611	annotation not available	Platelet derived growth factor receptor alpha.	0.425
ENSSARP00000003522	PIR	ENSSARP00000003522	ENSSARP00000001026	annotation not available	Pirin.	0.726
ENSSARP00000006909	PIR	ENSSARP00000006909	ENSSARP00000001026	annotation not available	Pirin.	0.827
ENSSARP00000009243	PIR	ENSSARP00000009243	ENSSARP00000001026	annotation not available	Pirin.	0.631
ENSSARP00000011457	ENSSARP00000003522	ENSSARP00000011457	ENSSARP00000003522	annotation not available	annotation not available	0.429
ENSSARP00000011457	FLT1	ENSSARP00000011457	ENSSARP00000000816	annotation not available	Fms related tyrosine kinase 1.	0.400
ENSSARP00000011457	FLT3	ENSSARP00000011457	ENSSARP00000009433	annotation not available	Fms related tyrosine kinase 3.	0.471
ENSSARP00000011457	KDR	ENSSARP00000011457	ENSSARP00000012971	annotation not available	Kinase insert domain receptor.	0.400
ENSSARP00000011457	PDGFRA	ENSSARP00000011457	ENSSARP00000001611	annotation not available	Platelet derived growth factor receptor alpha.	0.443
ENSSARP00000011457	PIR	ENSSARP00000011457	ENSSARP00000001026	annotation not available	Pirin.	0.665
FLT1	ENSSARP00000003522	ENSSARP00000000816	ENSSARP00000003522	Fms related tyrosine kinase 1.	annotation not available	0.447
FLT1	ENSSARP00000011457	ENSSARP00000000816	ENSSARP00000011457	Fms related tyrosine kinase 1.	annotation not available	0.400
FLT1	PIR	ENSSARP00000000816	ENSSARP00000001026	Fms related tyrosine kinase 1.	Pirin.	0.650
FLT3	ENSSARP00000003522	ENSSARP00000009433	ENSSARP00000003522	Fms related tyrosine kinase 3.	annotation not available	0.433
FLT3	ENSSARP00000011457	ENSSARP00000009433	ENSSARP00000011457	Fms related tyrosine kinase 3.	annotation not available	0.471
FLT3	PIR	ENSSARP00000009433	ENSSARP00000001026	Fms related tyrosine kinase 3.	Pirin.	0.650