Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
NSD2Nuclear receptor binding SET domain protein 2. (1361 aa)    
Predicted Functional Partners:
RRP8
Ribosomal RNA processing 8.
   
  0.922
TP53
Tumor protein p53.
    
 0.871
BRD2
Bromodomain containing 2.
    
 0.867
HDAC2
Histone deacetylase 2.
   
 0.864
HDAC1
Histone deacetylase 1.
   
 0.864
RPL8
Ribosomal protein L8.
    
 
 0.835
ENSSARP00000010657
annotation not available
    
 0.819
RBX1
Ring-box 1.
    
  0.819
ENSSARP00000002718
annotation not available
    
   0.817
RPL3
Ribosomal protein L3.
    
   0.804
Your Current Organism:
Sorex araneus
NCBI taxonomy Id: 42254
Other names: Eurasian shrew, European shrew, S. araneus
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