LRRC17 protein (Sorex araneus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Co-occurrence

Co-expression

Experiments

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Textmining

[Homology]

Score

LRRC17

Leucine rich repeat containing 17. (436 aa)

Predicted Functional Partners:

DIRAS2

0.904

ENSSARP00000005431

0.768

ENSSARP00000009965

0.745

HABP2

0.653

RAP2C

0.651

ENSSARP00000004095

0.623

INSRR

0.623

ENSSARP00000001844

0.621

ENSSARP00000000124

0.602

ENSSARP00000000264

0.602

Your Current Organism:

Sorex araneus

NCBI taxonomy Id: 42254
Other names: Eurasian shrew, European shrew, S. araneus

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TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

... network coordinates:

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DIRAS2	ENSSARP00000000124	ENSSARP00000001625	ENSSARP00000000124	DIRAS family GTPase 2.	annotation not available	0.695
DIRAS2	ENSSARP00000000264	ENSSARP00000001625	ENSSARP00000000264	DIRAS family GTPase 2.	annotation not available	0.695
DIRAS2	ENSSARP00000001844	ENSSARP00000001625	ENSSARP00000001844	DIRAS family GTPase 2.	annotation not available	0.667
DIRAS2	ENSSARP00000005431	ENSSARP00000001625	ENSSARP00000005431	DIRAS family GTPase 2.	annotation not available	0.879
DIRAS2	ENSSARP00000009965	ENSSARP00000001625	ENSSARP00000009965	DIRAS family GTPase 2.	annotation not available	0.741
DIRAS2	LRRC17	ENSSARP00000001625	ENSSARP00000001039	DIRAS family GTPase 2.	Leucine rich repeat containing 17.	0.904
ENSSARP00000000124	DIRAS2	ENSSARP00000000124	ENSSARP00000001625	annotation not available	DIRAS family GTPase 2.	0.695
ENSSARP00000000124	ENSSARP00000001844	ENSSARP00000000124	ENSSARP00000001844	annotation not available	annotation not available	0.591
ENSSARP00000000124	ENSSARP00000005431	ENSSARP00000000124	ENSSARP00000005431	annotation not available	annotation not available	0.598
ENSSARP00000000124	ENSSARP00000009965	ENSSARP00000000124	ENSSARP00000009965	annotation not available	annotation not available	0.566
ENSSARP00000000124	LRRC17	ENSSARP00000000124	ENSSARP00000001039	annotation not available	Leucine rich repeat containing 17.	0.602
ENSSARP00000000124	RAP2C	ENSSARP00000000124	ENSSARP00000008139	annotation not available	RAP2C, member of RAS oncogene family.	0.426
ENSSARP00000000264	DIRAS2	ENSSARP00000000264	ENSSARP00000001625	annotation not available	DIRAS family GTPase 2.	0.695
ENSSARP00000000264	ENSSARP00000001844	ENSSARP00000000264	ENSSARP00000001844	annotation not available	annotation not available	0.591
ENSSARP00000000264	ENSSARP00000005431	ENSSARP00000000264	ENSSARP00000005431	annotation not available	annotation not available	0.598
ENSSARP00000000264	ENSSARP00000009965	ENSSARP00000000264	ENSSARP00000009965	annotation not available	annotation not available	0.566
ENSSARP00000000264	LRRC17	ENSSARP00000000264	ENSSARP00000001039	annotation not available	Leucine rich repeat containing 17.	0.602
ENSSARP00000000264	RAP2C	ENSSARP00000000264	ENSSARP00000008139	annotation not available	RAP2C, member of RAS oncogene family.	0.426
ENSSARP00000001844	DIRAS2	ENSSARP00000001844	ENSSARP00000001625	annotation not available	DIRAS family GTPase 2.	0.667
ENSSARP00000001844	ENSSARP00000000124	ENSSARP00000001844	ENSSARP00000000124	annotation not available	annotation not available	0.591