Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
DUSP3Dual specificity phosphatase 3. (185 aa)    
Predicted Functional Partners:
VRK3
VRK serine/threonine kinase 3.
    
 0.991
LRP6
LDL receptor related protein 6.
    
 0.989
ENSSARP00000010428
annotation not available
    
 0.985
MAPK8
Mitogen-activated protein kinase 8.
    
 0.964
ENSSARP00000005728
annotation not available
    
 0.951
MAPK1
Mitogen-activated protein kinase 1.
    
 0.859
ERLIN2
ER lipid raft associated 2.
   
   0.849
ENSSARP00000004808
annotation not available
    
 0.814
LRP2
LDL receptor related protein 2.
    
 0.814
ENSSARP00000001376
annotation not available
    
  0.812
Your Current Organism:
Sorex araneus
NCBI taxonomy Id: 42254
Other names: Eurasian shrew, European shrew, S. araneus
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