STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ME1Malic enzyme 1. (545 aa)    
Predicted Functional Partners:
MDH1
Malate dehydrogenase 1.
  
 0.947
FH
Fumarate hydratase.
  
 
 0.945
ENSSARP00000002560
annotation not available
   
 0.940
MDH2
Malate dehydrogenase 2.
  
 0.937
PKLR
Pyruvate kinase L/R.
  
 0.926
PARP6
poly(ADP-ribose) polymerase family member 6.
  
 0.914
PKM
Pyruvate kinase M1/2.
  
 0.914
PDHB
Pyruvate dehydrogenase E1 beta subunit.
  
 
 0.907
ENSSARP00000002324
annotation not available
  
 0.900
ENSSARP00000009135
annotation not available
  
 0.896
Your Current Organism:
Sorex araneus
NCBI taxonomy Id: 42254
Other names: Eurasian shrew, European shrew, S. araneus
Server load: medium (52%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.