Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
IREB2Iron responsive element binding protein 2. (927 aa)    
Predicted Functional Partners:
FBXL5
F-box and leucine rich repeat protein 5.
    
 0.993
IDH1
Isocitrate dehydrogenase (NADP(+)) 1.
  
 0.966
ENSSARP00000009135
annotation not available
  
 0.960
ENSSARP00000012042
annotation not available
  
 0.960
SENP8
SUMO peptidase family member, NEDD8 specific.
  
 
 0.921
RBCK1
RANBP2-type and C3HC4-type zinc finger containing 1.
   
 
 0.919
FH
Fumarate hydratase.
  
 0.892
SUCLG1
succinate-CoA ligase alpha subunit.
  
 0.885
CIAO2A
Cytosolic iron-sulfur assembly component 2A.
    
 
 0.863
ENSSARP00000010896
annotation not available
  
 0.862
Your Current Organism:
Sorex araneus
NCBI taxonomy Id: 42254
Other names: Eurasian shrew, European shrew, S. araneus
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