Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
CASKCalcium/calmodulin dependent serine protein kinase. (926 aa)    
Predicted Functional Partners:
APBA1
Amyloid beta precursor protein binding family A member 1.
   
 0.997
SDC2
Syndecan 2.
    
 0.977
ENSSARP00000003725
annotation not available
   
 0.977
LIN7C
Lin-7 homolog C, crumbs cell polarity complex component.
    
 0.975
LIN7B
Lin-7 homolog B, crumbs cell polarity complex component.
    
 0.975
DLG2
Discs large MAGUK scaffold protein 2.
   
 0.959
DLG1
Discs large MAGUK scaffold protein 1.
   
 0.959
ENSSARP00000001903
annotation not available
   
 0.947
ENSSARP00000008638
annotation not available
    
 
 0.947
DLG3
Discs large MAGUK scaffold protein 3.
   
 0.928
Your Current Organism:
Sorex araneus
NCBI taxonomy Id: 42254
Other names: Eurasian shrew, European shrew, S. araneus
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