Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
MECRMitochondrial trans-2-enoyl-CoA reductase. (371 aa)    
Predicted Functional Partners:
ACADM
acyl-CoA dehydrogenase medium chain.
  
 0.962
ACADVL
acyl-CoA dehydrogenase very long chain.
  
 0.953
ACAA2
acetyl-CoA acyltransferase 2.
    
 0.946
HADHB
hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta.
    
 0.923
PPT2
Palmitoyl-protein thioesterase 2.
    
 0.903
LIPT1
Lipoyltransferase 1.
    
 0.841
SNX4
Sorting nexin 4.
   
   0.811
SNX7
Sorting nexin 7.
    
   0.798
ENSSARP00000002379
annotation not available
  
 0.786
NDUFAB1
NADH:ubiquinone oxidoreductase subunit AB1.
  
 0.766
Your Current Organism:
Sorex araneus
NCBI taxonomy Id: 42254
Other names: Eurasian shrew, European shrew, S. araneus
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