Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ENSSARP00000001189annotation not available (743 aa)    
Predicted Functional Partners:
CRKL
CRK like proto-oncogene, adaptor protein.
    
 
 0.963
NCK1
NCK adaptor protein 1.
    
 
 0.949
GRB2
Growth factor receptor bound protein 2.
    
 
 0.948
CRK
CRK proto-oncogene, adaptor protein.
    
 
 0.946
EGFR
Epidermal growth factor receptor.
    
   0.944
MAP4K3
Mitogen-activated protein kinase kinase kinase kinase 3.
    
   0.861
PPP4C
Protein phosphatase 4 catalytic subunit.
    
 
 0.803
MAP3K11
Mitogen-activated protein kinase kinase kinase 11.
    
 
 0.777
BLNK
B cell linker.
    
 
 0.771
MAP4K5
Mitogen-activated protein kinase kinase kinase kinase 5.
      
 0.641
Your Current Organism:
Sorex araneus
NCBI taxonomy Id: 42254
Other names: Eurasian shrew, European shrew, S. araneus
Server load: medium (42%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.