DIS3L protein (Sorex araneus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Co-occurrence

Co-expression

Experiments

Databases

Textmining

[Homology]

Score

DIS3L

DIS3 like exosome 3'-5' exoribonuclease. (956 aa)

Predicted Functional Partners:

EXOSC1

0.998

ENSSARP00000000595

0.998

EXOSC4

0.998

EXOSC10

0.998

EXOSC8

0.998

EXOSC7

0.997

MPHOSPH6

0.997

ENSSARP00000009113

0.997

HBS1L

0.995

MTREX

0.994

Your Current Organism:

Sorex araneus

NCBI taxonomy Id: 42254
Other names: Eurasian shrew, European shrew, S. araneus

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DIS3L	ENSSARP00000000595	ENSSARP00000001232	ENSSARP00000000595	DIS3 like exosome 3'-5' exoribonuclease.	annotation not available	0.998
DIS3L	ENSSARP00000009113	ENSSARP00000001232	ENSSARP00000009113	DIS3 like exosome 3'-5' exoribonuclease.	annotation not available	0.997
DIS3L	EXOSC1	ENSSARP00000001232	ENSSARP00000000146	DIS3 like exosome 3'-5' exoribonuclease.	Exosome component 1.	0.998
DIS3L	EXOSC10	ENSSARP00000001232	ENSSARP00000011894	DIS3 like exosome 3'-5' exoribonuclease.	Exosome component 10.	0.998
DIS3L	EXOSC4	ENSSARP00000001232	ENSSARP00000010674	DIS3 like exosome 3'-5' exoribonuclease.	Exosome component 4.	0.998
DIS3L	EXOSC7	ENSSARP00000001232	ENSSARP00000004853	DIS3 like exosome 3'-5' exoribonuclease.	Exosome component 7.	0.997
DIS3L	EXOSC8	ENSSARP00000001232	ENSSARP00000012580	DIS3 like exosome 3'-5' exoribonuclease.	Exosome component 8.	0.998
DIS3L	HBS1L	ENSSARP00000001232	ENSSARP00000006121	DIS3 like exosome 3'-5' exoribonuclease.	HBS1 like translational GTPase.	0.995
DIS3L	MPHOSPH6	ENSSARP00000001232	ENSSARP00000006365	DIS3 like exosome 3'-5' exoribonuclease.	M-phase phosphoprotein 6.	0.997
DIS3L	MTREX	ENSSARP00000001232	ENSSARP00000007630	DIS3 like exosome 3'-5' exoribonuclease.	Mtr4 exosome RNA helicase.	0.994
ENSSARP00000000595	DIS3L	ENSSARP00000000595	ENSSARP00000001232	annotation not available	DIS3 like exosome 3'-5' exoribonuclease.	0.998
ENSSARP00000000595	ENSSARP00000009113	ENSSARP00000000595	ENSSARP00000009113	annotation not available	annotation not available	0.999
ENSSARP00000000595	EXOSC1	ENSSARP00000000595	ENSSARP00000000146	annotation not available	Exosome component 1.	0.999
ENSSARP00000000595	EXOSC10	ENSSARP00000000595	ENSSARP00000011894	annotation not available	Exosome component 10.	0.999
ENSSARP00000000595	EXOSC4	ENSSARP00000000595	ENSSARP00000010674	annotation not available	Exosome component 4.	0.998
ENSSARP00000000595	EXOSC7	ENSSARP00000000595	ENSSARP00000004853	annotation not available	Exosome component 7.	0.999
ENSSARP00000000595	EXOSC8	ENSSARP00000000595	ENSSARP00000012580	annotation not available	Exosome component 8.	0.998
ENSSARP00000000595	HBS1L	ENSSARP00000000595	ENSSARP00000006121	annotation not available	HBS1 like translational GTPase.	0.996
ENSSARP00000000595	MPHOSPH6	ENSSARP00000000595	ENSSARP00000006365	annotation not available	M-phase phosphoprotein 6.	0.997
ENSSARP00000000595	MTREX	ENSSARP00000000595	ENSSARP00000007630	annotation not available	Mtr4 exosome RNA helicase.	0.996