STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RUNX2RUNX family transcription factor 2. (589 aa)    
Predicted Functional Partners:
CBFB
Core-binding factor subunit beta.
    
 0.992
CDK6
Cyclin dependent kinase 6.
    
 0.931
YAP1
Yes associated protein 1.
    
 0.926
SMAD1
SMAD family member 1.
    
 0.914
ENSSARP00000002096
annotation not available
    
 0.911
ENSSARP00000003871
annotation not available
    
 0.911
ETS1
ETS proto-oncogene 1, transcription factor.
   
 0.908
ENSSARP00000007838
annotation not available
    
 0.871
ENSSARP00000009515
annotation not available
    
 0.871
ENSSARP00000008540
annotation not available
    
 0.868
Your Current Organism:
Sorex araneus
NCBI taxonomy Id: 42254
Other names: Eurasian shrew, European shrew, S. araneus
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.