Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PRKAA1Protein kinase AMP-activated catalytic subunit alpha 1. (513 aa)    
Predicted Functional Partners:
PRKAB1
Protein kinase AMP-activated non-catalytic subunit beta 1.
   
 0.999
PRKAG1
Protein kinase AMP-activated non-catalytic subunit gamma 1.
   
 0.999
PRKAB2
Protein kinase AMP-activated non-catalytic subunit beta 2.
   
 0.999
PRKAA2
Protein kinase AMP-activated catalytic subunit alpha 2.
   
 0.998
ENSSARP00000011186
annotation not available
   
 0.997
MAP3K7
Mitogen-activated protein kinase kinase kinase 7.
    
0.993
SESN2
Sestrin 2.
     
 0.991
CFTR
CF transmembrane conductance regulator.
    
 0.979
ENSSARP00000005763
annotation not available
    
 0.976
CAB39
Calcium binding protein 39.
    
 0.969
Your Current Organism:
Sorex araneus
NCBI taxonomy Id: 42254
Other names: Eurasian shrew, European shrew, S. araneus
Server load: low (32%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.