Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
NUDT15Nudix hydrolase 15. (163 aa)    
Predicted Functional Partners:
DPYD
Dihydropyrimidine dehydrogenase.
    
 0.858
ENSSARP00000002656
annotation not available
  
 
 0.844
GCH1
GTP cyclohydrolase 1.
  
 
 0.827
NUDT2
Nudix hydrolase 2.
  
 
 0.823
ENSSARP00000010512
annotation not available
      
 0.823
FPGS
Folylpolyglutamate synthase.
  
 
 0.816
DHODH
Dihydroorotate dehydrogenase (quinone).
    
 0.788
ENSSARP00000006702
annotation not available
    
 0.785
NAPRT
Nicotinate phosphoribosyltransferase.
    
 0.785
TYMS
Thymidylate synthetase.
    
 0.779
Your Current Organism:
Sorex araneus
NCBI taxonomy Id: 42254
Other names: Eurasian shrew, European shrew, S. araneus
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