Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
WASWASP actin nucleation promoting factor. (412 aa)    
Predicted Functional Partners:
NCK1
NCK adaptor protein 1.
    
 0.986
ARPC2
Actin related protein 2/3 complex subunit 2.
    
 0.986
ITSN2
Intersectin 2.
    
 0.985
ARPC3
Actin related protein 2/3 complex subunit 3.
    
 0.984
ACTR2
Actin related protein 2.
    
 0.982
ENSSARP00000000188
annotation not available
    
 0.972
GRB2
Growth factor receptor bound protein 2.
    
 0.972
WIPF2
WAS/WASL interacting protein family member 2.
   
 0.970
HCLS1
Hematopoietic cell-specific Lyn substrate 1.
   
 0.968
ENSSARP00000004682
annotation not available
   
 0.968
Your Current Organism:
Sorex araneus
NCBI taxonomy Id: 42254
Other names: Eurasian shrew, European shrew, S. araneus
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