STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CHEK2Checkpoint kinase 2. (553 aa)    
Predicted Functional Partners:
ATM
ATM serine/threonine kinase.
    
 0.995
ATR
ATR serine/threonine kinase.
    
 0.993
ENSSARP00000004303
annotation not available
   
0.992
TP53
Tumor protein p53.
    
 0.990
TP53BP1
Tumor protein p53 binding protein 1.
    
 0.987
CDC25C
Cell division cycle 25C.
   
 0.985
CDC25A
Cell division cycle 25A.
   
 0.984
BRCA1
BRCA1 DNA repair associated.
   
 0.967
ENSSARP00000004445
annotation not available
   
 0.956
CDC7
Cell division cycle 7.
    
 
 0.951
Your Current Organism:
Sorex araneus
NCBI taxonomy Id: 42254
Other names: Eurasian shrew, European shrew, S. araneus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.