Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ENSSARP00000001368annotation not available (72 aa)    
Predicted Functional Partners:
APOE
Apolipoprotein E.
    
 0.986
APLP2
Amyloid beta precursor like protein 2.
   
  0.975
PRNP
Prion protein.
   
 0.965
BACE1
Beta-secretase 1.
    
 0.958
ENSSARP00000010315
annotation not available
    
 
 0.940
TTR
Transthyretin.
    
 0.927
CRYAB
Crystallin alpha B.
   
 
 0.908
APBA1
Amyloid beta precursor protein binding family A member 1.
   
 
 0.901
ENSSARP00000008540
annotation not available
    
 0.898
DAB1
DAB adaptor protein 1.
    
 
 0.895
Your Current Organism:
Sorex araneus
NCBI taxonomy Id: 42254
Other names: Eurasian shrew, European shrew, S. araneus
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