Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LATS2Large tumor suppressor kinase 2. (1036 aa)    
Predicted Functional Partners:
LATS1
Large tumor suppressor kinase 1.
  
 
0.999
YAP1
Yes associated protein 1.
    
 0.999
SAV1
Salvador family WW domain containing protein 1.
    
 0.998
MOB1B
MOB kinase activator 1B.
   
 0.997
AJUBA
Ajuba LIM protein.
    
 0.995
STK3
Serine/threonine kinase 3.
    
0.995
AMOT
Angiomotin.
    
 0.992
MOB1A
MOB kinase activator 1A.
    
 0.991
ENSSARP00000008568
annotation not available
   
 0.985
NF2
Neurofibromin 2.
    
 
 0.977
Your Current Organism:
Sorex araneus
NCBI taxonomy Id: 42254
Other names: Eurasian shrew, European shrew, S. araneus
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