Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
EPHA2EPH receptor A2. (973 aa)    
Predicted Functional Partners:
EFNA5
Ephrin A5.
   
 0.995
EFNA1
Ephrin A1.
   
 0.995
EFNA3
Ephrin A3.
   
 0.988
CBL
Cbl proto-oncogene.
    
 0.957
ENSSARP00000008601
annotation not available
   
 0.953
EFNB2
Ephrin B2.
   
 0.914
EFNB1
Ephrin B1.
   
 0.905
EFNA4
Ephrin A4.
   
 0.882
PIK3R1
Phosphoinositide-3-kinase regulatory subunit 1.
    
 0.878
EFNB3
Ephrin B3.
   
 0.876
Your Current Organism:
Sorex araneus
NCBI taxonomy Id: 42254
Other names: Eurasian shrew, European shrew, S. araneus
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