STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
UBE2MUbiquitin conjugating enzyme E2 M. (183 aa)    
Predicted Functional Partners:
NEDD8
NEDD8 ubiquitin like modifier.
   
 0.998
UBA3
Ubiquitin like modifier activating enzyme 3.
    
 0.996
NAE1
NEDD8 activating enzyme E1 subunit 1.
    
 0.992
CUL3
Cullin 3.
    
 0.988
RBX1
Ring-box 1.
    
 0.987
DCUN1D1
Defective in cullin neddylation 1 domain containing 1.
    
 0.979
DCUN1D3
Defective in cullin neddylation 1 domain containing 3.
    
 0.978
RNF7
Ring finger protein 7.
    
 0.975
ENSSARP00000007617
annotation not available
    
 0.966
UBA1
Ubiquitin like modifier activating enzyme 1.
    
 0.955
Your Current Organism:
Sorex araneus
NCBI taxonomy Id: 42254
Other names: Eurasian shrew, European shrew, S. araneus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.