LIPI protein (Sorex araneus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Co-occurrence

Co-expression

Experiments

Databases

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[Homology]

Score

LIPI

Lipase I. (443 aa)

Predicted Functional Partners:

LIPM

0.660

LIPN

0.650

MYSM1

0.611

ENSSARP00000012632

0.569

ENSSARP00000006823

0.567

KDM2A

0.521

ENSSARP00000007374

0.521

ENSSARP00000001028

0.475

SPOP

0.475

ARID4A

0.471

Your Current Organism:

Sorex araneus

NCBI taxonomy Id: 42254
Other names: Eurasian shrew, European shrew, S. araneus

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TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

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structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

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node degree of proteins in your network (given the current score cut-off)

... network coordinates:

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a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ARID4A	ENSSARP00000007374	ENSSARP00000006346	ENSSARP00000007374	AT-rich interaction domain 4A.	annotation not available	0.548
ARID4A	KDM2A	ENSSARP00000006346	ENSSARP00000001674	AT-rich interaction domain 4A.	Lysine demethylase 2A.	0.548
ARID4A	LIPI	ENSSARP00000006346	ENSSARP00000001538	AT-rich interaction domain 4A.	Lipase I.	0.471
ARID4A	MYSM1	ENSSARP00000006346	ENSSARP00000002751	AT-rich interaction domain 4A.	Myb like, SWIRM and MPN domains 1.	0.850
ENSSARP00000001028	LIPI	ENSSARP00000001028	ENSSARP00000001538	annotation not available	Lipase I.	0.475
ENSSARP00000001028	MYSM1	ENSSARP00000001028	ENSSARP00000002751	annotation not available	Myb like, SWIRM and MPN domains 1.	0.483
ENSSARP00000001028	SPOP	ENSSARP00000001028	ENSSARP00000011953	annotation not available	Speckle type BTB/POZ protein.	0.909
ENSSARP00000006823	ENSSARP00000007374	ENSSARP00000006823	ENSSARP00000007374	annotation not available	annotation not available	0.648
ENSSARP00000006823	KDM2A	ENSSARP00000006823	ENSSARP00000001674	annotation not available	Lysine demethylase 2A.	0.648
ENSSARP00000006823	LIPI	ENSSARP00000006823	ENSSARP00000001538	annotation not available	Lipase I.	0.567
ENSSARP00000007374	ARID4A	ENSSARP00000007374	ENSSARP00000006346	annotation not available	AT-rich interaction domain 4A.	0.548
ENSSARP00000007374	ENSSARP00000006823	ENSSARP00000007374	ENSSARP00000006823	annotation not available	annotation not available	0.648
ENSSARP00000007374	LIPI	ENSSARP00000007374	ENSSARP00000001538	annotation not available	Lipase I.	0.521
ENSSARP00000007374	MYSM1	ENSSARP00000007374	ENSSARP00000002751	annotation not available	Myb like, SWIRM and MPN domains 1.	0.614
ENSSARP00000012632	LIPI	ENSSARP00000012632	ENSSARP00000001538	annotation not available	Lipase I.	0.569
KDM2A	ARID4A	ENSSARP00000001674	ENSSARP00000006346	Lysine demethylase 2A.	AT-rich interaction domain 4A.	0.548
KDM2A	ENSSARP00000006823	ENSSARP00000001674	ENSSARP00000006823	Lysine demethylase 2A.	annotation not available	0.648
KDM2A	LIPI	ENSSARP00000001674	ENSSARP00000001538	Lysine demethylase 2A.	Lipase I.	0.521
KDM2A	MYSM1	ENSSARP00000001674	ENSSARP00000002751	Lysine demethylase 2A.	Myb like, SWIRM and MPN domains 1.	0.614
LIPI	ARID4A	ENSSARP00000001538	ENSSARP00000006346	Lipase I.	AT-rich interaction domain 4A.	0.471