Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
HPS3HPS3 biogenesis of lysosomal organelles complex 2 subunit 1. (998 aa)    
Predicted Functional Partners:
HPS5
HPS5 biogenesis of lysosomal organelles complex 2 subunit 2.
   
 0.998
BLOC1S6
Biogenesis of lysosomal organelles complex 1 subunit 6.
     
 0.971
STX12
Syntaxin 12.
     
 0.927
SNAP25
Synaptosome associated protein 25.
     
 0.924
WASHC4
WASH complex subunit 4.
     
  0.921
ENSSARP00000012139
annotation not available
     
 0.893
LOC101539215
SNARE-associated protein Snapin.
     
 0.893
ENSSARP00000009276
annotation not available
     
  0.891
TECPR2
Tectonin beta-propeller repeat containing 2.
   
 0.873
PI4K2B
Phosphatidylinositol 4-kinase type 2 beta.
     
  0.855
Your Current Organism:
Sorex araneus
NCBI taxonomy Id: 42254
Other names: Eurasian shrew, European shrew, S. araneus
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