STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
GJA1Gap junction protein alpha 1. (227 aa)    
Predicted Functional Partners:
TJP1
Tight junction protein 1.
   
 0.999
YES1
YES proto-oncogene 1, Src family tyrosine kinase.
    
 0.987
ENSSARP00000010428
annotation not available
    
 0.965
ENSSARP00000008126
annotation not available
    
 0.959
ENSSARP00000012120
annotation not available
    
 
 0.945
GJB2
Gap junction protein beta 2.
    
 0.937
EPS15
Epidermal growth factor receptor pathway substrate 15.
    
 
 0.933
ENSSARP00000001626
annotation not available
    
 0.933
GJB1
Gap junction protein beta 1.
    
 0.932
ENSSARP00000001835
annotation not available
    
 0.929
Your Current Organism:
Sorex araneus
NCBI taxonomy Id: 42254
Other names: Eurasian shrew, European shrew, S. araneus
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.